Subject(s)
Deafness/etiology , Deafness/surgery , Adolescent , Adult , Cochlear Implants , Female , Humans , Male , Mexico , Middle Aged , Otosclerosis , Stapes SurgeryABSTRACT
BACKGROUND: A method is needed to measure parameters of vertigo and disequilibrium. Our objective was to ascertain whether the vestibular autorotation test (VAT) gives numerical data on the vestibular oculomotor reflex (VOR) that are useful for clinical research. METHODS: A VAT was carried out on 17 healthy young volunteers twice, with an interval of 7 days (group A), and on a single occasion on another 17 volunteers of similar age and health (group B). The parameters studied were vertical and horizontal gains and phases and horizontal eye velocity symmetry. The resulting values were paired inter-session in the same individuals of group A, and between the first test of group A with the test in group B, chosen at random. Variances for the sets of numbers in each parameter as a whole and for each frequency of stimulation were calculated and statistical validity was determined. RESULTS: No significant differences were found between the inter-session and inter-individual results. Variances of gain (horizontal and vertical) were small, but variances of phase and symmetry were large. An analysis of frequencies of stimulation revealed that variances increased with the elevation of frequency. CONCLUSIONS: For clinical research and evaluation, the VAT affords sufficiently consistent figures for vertical and horizontal gain in the entire spectrum of frequencies tested (2-5.9 Hz) and for horizontal phases between 2-3.9 Hz. Vertical phases and horizontal asymmetry vary too greatly for our stated purpose.
Subject(s)
Reflex, Vestibulo-Ocular/physiology , Vestibular Function Tests/statistics & numerical data , Adult , Analysis of Variance , Female , Humans , Male , Middle Aged , Research , Vestibular Function Tests/methodsABSTRACT
Se reporta el caso de una paciente con presentación simultánea de paraganglioma timpánico y adenoma hipofisiario. Esta asociación puede representar una variedad del síndrome de neoplasia endócrina múltiple (NEM) tipo I que no ha sido descrita. Los paragangliomas timpánicos están embriológicamente relacionados a los feocromocitomas que pueden formar parte del síndrome de NEW tipo II. Los paragangliomas y los adenomas hipofisiarios se derivan de la cresta neural y pueden corresponder al síndrome de NEW tipo II y tipo y tipo I respectivamente. Estos tumores se presentan con un patrón de herancia autosómico dominante, y se ha reportado que ocurre cierta sobreposición entre los tumores del síndrome de NEM Tipo I y Tipo II
Subject(s)
Humans , Female , Aged , Adenoma , Pituitary Gland/pathology , Multiple Endocrine Neoplasia/diagnosis , Ear, Middle/pathology , Paraganglioma , Pituitary Neoplasms/diagnosis , Pituitary Neoplasms/surgery , Magnetic Resonance SpectroscopyABSTRACT
The vestibulo-ocular reflex was studied at high frequencies of active head rotation (2 to 6 Hz) in twenty-three patients with benign positional vertigo (BPPV). Gain and phase measurements were obtained in the vertical and horizontal planes, and the results were compared to those of a control group consisting of 19 asymptomatic age-matched subjects. In the horizontal plane, the phase lead was significantly smaller in patients with BPPV as compared to controls (p < 0.01 at all frequencies). Vertical results did not differ from normals. These findings challenge "cupulolithiasis" as an explanation of the mechanism of BPPV's symptoms.
Subject(s)
Ear, Inner/surgery , Meniere Disease/surgery , Reflex, Vestibulo-Ocular/physiology , Vestibular Nerve/surgery , Adult , Aged , Ear, Inner/physiopathology , Female , Humans , Male , Meniere Disease/physiopathology , Middle Aged , Vestibular Nerve/physiopathologyABSTRACT
A group of patients with congenital endotropia or exotropia was investigated in their capacity to perform reflex eye movements. Some patients had a successful surgical correction of their eye defect. The functions measured were the vestibulo-oculomotor reflex, the feedback control loop for searching and following eye movements and the optomotor reflex. A loss in the functional capacity was displayed in all the tests done. The average value of the losses found for the whole group, according to the test used, were from 8 to 27% for the vestibulo-oculomotor reflex; 22 to 42% for the eye tracking feedback loop, and 48% for the optomotor reflex. The deficit was not due to the incorrect eye position, because the successfully operated subjects had the same magnitude of the motor defect than the non-operated patients.
